Which organization mandates the use of CITI training for researchers?

The correct answer highlights the role of the Department of Health and Human Services (HHS) in establishing guidelines for the ethical conduct of research involving human subjects. HHS oversees several agencies, including the National Institutes of Health (NIH) and the Office for Human Research Protections (OHRP), which promote and enforce regulations regarding research ethics. CITI training is widely used in the research community to ensure that researchers are educated about the ethical considerations and regulatory requirements for conducting research involving human subjects.

While the NIH is a significant contributor to the promotion of ethical training and often encourages CITI training, it does not mandate it in the same way that HHS sets the broader regulatory framework. The FDA is concerned with drug and medical device safety, and the WHO focuses on global health standards, but neither organization directly mandates CITI training for researchers. Thus, the HHS's oversight role makes it the organization that establishes the necessity of such training.