CITI Training Practice Exam

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What is determined for a drug in the preclinical phase?

Market potential
Pharmacokinetics and bioavailability
Clinical trial protocols
FDA approval status

The correct answer is: Pharmacokinetics and bioavailability

During the preclinical phase of drug development, extensive testing is done to evaluate the potential efficacy and safety of the drug. This includes determining the drug's pharmacokinetics, or how it is absorbed, distributed, metabolized, and excreted in the body. It also includes assessing its bioavailability, or the rate and extent to which the drug reaches the target site in the body. This information is crucial in determining the drug's potential for success and suitability for further development. Market potential, clinical trial protocols, and FDA approval status are not determined during the preclinical phase, as they are dependent on the results and data gathered during this phase.